The SRA employs washed donor platelets and detects their activation by measuring the release of endogenous serotonin induced by addition of patient serum. The serotonin levels are …

Few laboratory tests are as clinically useful as The platelet serotonin-release assay (SRA): a positive SRA in the appropriate clinical context is virtually diagnostic of heparin-induced …

2011年12月10日 · Platelet activation assays, such as the serotonin-release assay, are superior to PF4-dependent immunoassays in discerning which heparin-induced antibodies are clinically …

The SRA is a functional assay used to diagnose HIT. It identifies pathogenic IgG antibodies capable of binding and cross-linking platelet Fc gamma RIIA and triggering platelet activation. …

In a negative serotonin release assay (SRA), patient serum induced serotonin release of below 20% from normal donor platelets in presence of low concentration of unfractionated heparin …

Our serotonin release assay is the gold standard diagnostic test for detecting clinically relevant (platelet-activating) heparin-induced thrombocytopenia (HIT) antibodies.

The SRA test is a functional assay that measures heparin-dependent platelet activation. Patient serum is incubated with donor platelets containing radiolabeled serotonin and different …

Serotonin Release Assay Features and Benefits. Gold-standard confirmatory test; Complex, highly sensitive and specific functional assay that uses high-performance liquid …

Few laboratory tests are as clinically useful as the platelet serotonin-release assay (SRA): a positive SRA in the appropriate clinical context is virtually diagnostic of heparin-induced …

Test Information: The serotonin release assay is designed to detect heparin-dependent platelet antibodies in the serum from patients suspected of having Heparin-Induced Thrombocytopenia …