Single-cell chromatin accessibility reveals principles of …
2015年6月17日 · We have developed a single-cell assay for transposase-accessible chromatin (scATAC-seq). ATAC-seq is an ensemble measure of open chromatin that uses the …
Systematic benchmarking of single-cell ATAC-sequencing …
2023年8月3日 · In this study, we benchmark the performance of eight scATAC-seq methods across 47 experiments using human peripheral blood mononuclear cells (PBMCs) as a …
Analyzing PBMC scATAC-seq • Signac - Stuart Lab
2024年8月20日 · To help interpret the scATAC-seq data, we can classify cells based on an scRNA-seq experiment from the same biological system (human PBMC). We utilize methods …
Scalable and unbiased sequence-informed embedding of single
2024年5月9日 · Standard scATAC sequencing (scATAC-seq) analysis pipelines represent cells as sparse numeric vectors relative to an atlas of peaks or genomic tiles and consequently ignore …
Fundamental and practical approaches for single-cell ATAC-seq …
Assays for transposase-accessible chromatin through high-throughput sequencing (ATAC-seq) are effective tools in the study of genome-wide chromatin accessibility landscapes.
scATACpipe: A nextflow pipeline for comprehensive and …
Single cell ATAC-seq (scATAC-seq) has become the most widely used method for profiling open chromatin landscape of heterogeneous cell populations at a single-cell resolution.
Single-cell ATAC-seq signal extraction and enhancement with …
2020年7月3日 · Single-cell sequencing assay for transposase-accessible chromatin (scATAC-seq) is the state-of-the-art technology for analyzing genome-wide regulatory landscapes in …
Single-cell ATAC sequencing analysis: From data preprocessing …
2020年6月12日 · In this review, we discuss scATAC-seq technology and data analysis methods, ranging from preprocessing to downstream analysis, along with an up-to-date list of published …
scATAC-pro: a comprehensive workbench for single-cell …
2020年4月20日 · Here, we present scATAC-pro for quality assessment, analysis, and visualization of single-cell chromatin accessibility sequencing data. scATAC-pro computes a …
How scATAC-seq works - Single Cell Discoveries
2023年10月23日 · Single-cell ATAC-seq (scATAC-seq) is the leading new technology for analyzing a cell’s epigenetic traits, specifically the chromatin accessibility profiles of single …