During hemofiltration, a patient's blood is passed through a set of tubing (a filtration circuit) via a machine to a semipermeable membrane (the filter) where waste products and water (collectively called ultrafiltrate) are removed by convection. Replacement fluid is added and the blood is returned to the patient.

Diffusive therapy (hemodialysis) removes small solutes mainly, whereas convective therapies (hemofiltration and hemodiafiltration) may also eliminate larger molecules such as myoglobin or cytokines. Conversely, convective therapies might predispose patients to filter clotting and thus increased costs.

2017年3月14日 · 血液滤过(hemofiltration, HF) ☘ 原理. 如果把血透比作「人工肾」，那么血滤则是「人工肾小球」。血液通过机器泵或者血压流经体外滤器，在「人 工肾小球」跨膜压的作用下，液体从压力高的一侧向压力低的一侧移动，通过对流的方式获得超滤液。但只有肾小球是 ...

Hemofiltration is a method whereby the removal of a compound occurs primarily by convective solute transport, rather than diffusion. It is performed using highly permeable membranes, with replenishment of the fluid or plasma water removed during treatment.

Despite similar clearance of small molecules, hemofiltration is reported to achieve higher clearance of medium-sized to larger molecules compared to hemodialysis . Consequently, it is postulated that hemofiltration might benefit critically ill patients with AKI by better clearing large toxic inflammatory cytokines .

2012年8月6日 · Data primarily from crossover RCTs suggested that hemofiltration increased clearance of medium to larger molecules, including inflammatory cytokines, compared to hemodialysis, although almost no studies measured changes in serum concentrations. Meta-analyses were based on very limited data.

2000年10月20日 · Since its first description continuous hemofiltration, or `continuous renal replacement therapy' (CRRT) as it is now called, has undergone remarkable growth . In the modern ICU, CRRT is now performed using pump technology and …

In continuous hemofiltration, water and solutes filter from the blood by convection through a permeable membrane; the filtrate is discarded, and the patient must receive infusions of physiologically balanced water and electrolytes. A dialysis circuit can be added to the filter to improve solute clearance. Procedures may be . Arteriovenous ...

2018年4月9日 · HEMOFILTRATION (HF) In comparison to diffusion-based HD, HF relies on convection through a larger pore hemofilter. The key difference is the absence of dialysate. Instead, pressure is applied across this hemofilter, and solutes are pushed through the membrane along with plasma water.

血液滤过（HF）是指在血液净化过程中不使用透析液，而是在血管通路中持续补充一定量的置换液，与血液充分混合，再以相同的速度进行超滤，以达到清除体内过多的水和毒素的目的。 与血液透析相比，血液滤过具有对血流动力学影响小、中分子物质清除率高等优点。 1.高血容量所致心力衰竭、急性肺水肿。 2.高肾素型顽固性高血压。 3.严重水、电解质紊乱，酸碱失衡，严重代谢性酸中毒、严重代谢性碱中毒、高钠或低钠血症、严重高血钾或低血钾等。 4.药物或毒物中毒，尤其 …