Gastrinomas are neuroendocrine tumors (NETs), usually located in the duodenum or pancreas, that secrete gastrin and cause a clinical syndrome known as Zollinger–Ellison syndrome (ZES). [1][2][3] A large number of gastrinomas develop in the pancreas or duodenum, with near-equal frequency, and approximately 10% arise as primary neoplasms in lymph ...

2018年9月18日 · If you have a gastrinoma, your body secretes large amounts of gastrin, resulting in a higher level of stomach acid. This higher level can cause the formation of ulcers in your stomach and small...

2023年7月28日 · Gastrinomas are neuroendocrine tumors characterized by the secretion of gastrin with resultant excessive gastric acid production, causing severe peptic ulcer disease and diarrhea, a combination referred to as the Zollinger-Ellison syndrome (ZES). Gastrinomas are the most common functional and malignant pancreatic endocrine tumors.

2025年1月6日 · Gastrinomas are rare, usually small tumors that can originate from G cells in the pancreas, stomach or small intestine. Most gastrinomas are malignant. Gastrinomas can be solitary or develop in clusters, and can occur sporadically or be associated with multiple endocrine neoplasia type 1 (MEN-1).

A gastrinoma is a gastrin-producing tumor usually located in the pancreas or the duodenal wall. Gastric acid hypersecretion and aggressive, refractory peptic ulceration result (Zollinger-Ellison syndrome). Diagnosis is by measuring serum gastrin levels. Treatment is proton pump inhibitors and surgical removal.

A gastrinoma is a gastrin-producing tumor usually located in the pancreas or the duodenal wall. Gastric acid hypersecretion and aggressive, refractory peptic ulceration result (Zollinger-Ellison syndrome). Diagnosis is by measuring serum gastrin levels. Treatment is proton pump inhibitors and surgical removal.

A gastrinoma is a neuroendocrine tumor that produces excessive levels of the hormone gastrin, which stimulates the stomach to secrete acid and enzymes, causing peptic ulcers. Gastrinomas are usually located in the pancreas or duodenum (the first segment of the small intestine).

2021年12月3日 · A gastrinoma is a gastrin-secreting tumor that can occur in the pancreas, although it is most commonly found in the duodenum. Duodenal wall gastrinomas have been identified in 40-50% of patients.

2023年9月27日 · Presently, the term gastrinoma and ZES are often used synonymous, however, in the past the term gastrinoma was also used to refer to a neoplasm synthesizing gastrin and ZES to the clinical manifestations .

Zollinger-Ellison syndrome (ZES) is caused by secretion of gastrin by duodenal or pancreatic neuroendocrine tumors (gastrinomas). The annual incidence of gastrinomas is 0.5 to 2 per million population [3-5]. Most patients are diagnosed between the ages of 20 and 50, with a higher incidence in males as compared with females [6].