Caspases in cell death, inflammation and disease - PMC
Caspases are an evolutionary conserved family of cysteine proteases that are centrally involved in cell death and inflammation responses. A wealth of foundational insight into the molecular …
Caspase Functions in Cell Death and Disease - PMC - PubMed …
Caspases are key regulators of apoptosis and inflammation. Insufficient caspase activation can promote tumorigenesis or infection; hyperactivation can promote neurodegeneration or …
Caspase - an overview | ScienceDirect Topics
Caspase refers to a family of cysteine proteases that are Ced-3 homologues and play a crucial role in apoptosis. They are initially produced as inactive proforms and become active after …
Caspases in Cell Death, Inflammation, and Disease - Cell Press
Caspases are an evolutionary conserved family of cysteine proteases that are centrally involved in cell death and inflammation responses. A wealth of foundational insight into the molecular …
Caspases in Cell Death, Inflammation, and Disease - PubMed
2019年6月18日 · Caspases are an evolutionary conserved family of cysteine proteases that are centrally involved in cell death and inflammation responses. A wealth of foundational insight …
Caspases in Cell Death, Inflammation, and Disease
2019年6月18日 · Caspases are an evolutionary conserved family of cysteine proteases that are centrally involved in cell death and inflammation responses. A wealth of foundational insight …
A Primer on Caspase Mechanisms - PMC - PubMed Central (PMC)
Caspase-11 was the first enzyme discovered to participate in a non-canonical or non-caspase-1 mediated inflammasome as a response to gram-negative bacteria. This then led to the …
Caspases and their substrates | Cell Death & Differentiation - Nature
2017年5月12日 · The human caspase family is divided into three main groups, primarily based on sequence similarity and biological function. 15 Group I comprises the inflammatory caspases …
Caspbase
Welcome to the CaspBase – the Caspase Sequence Database. Caspases (cysteinyl aspartate-specific proteases) are an ancient class of enzymes that maintain cellular homeostasis by …
Caspase-6 Is a Key Regulator of Innate Immunity, Inflammasome ...
2020年4月30日 · Caspases regulate cell death, immune responses, and homeostasis. Caspase-6 is categorized as an executioner caspase but shows key differences from the other …
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