CD154, also called CD40 ligand or CD40L, is a protein that is primarily expressed on activated T cells [5] and is a member of the TNF superfamily of molecules. It binds to CD40 on antigen …

Over time, many features and purposes of the CD40 signaling pathway were discovered, including the discovery of CD40 ligand (CD154/CD40L), a T cell surface molecule which is …

CD40 ligand (CD40L) is a 261-amino-acid membrane glycoprotein expressed on activated CD4 lymphocytes. Expression occurs shortly after T cell activation. The natural ligand for CD40L is …

CD40 and CD40 ligand (CD40L) have been well-documented as stimulatory immune checkpoint and play a broad role in various immunological processes contributing to both humoral and cell …

CD40 binds its ligand CD40L, which is transiently expressed on T cells and other non-immune cells under inflammatory conditions. A wide spectrum of molecular and cellular processes is …

This article reviews recent developments in this field of research, with main emphasis on (1) structure and expression of CD40 and its ligand; (2) CD40 signal transduction; (3) in vitro …

The ligand for CD40, CD154 (also known as TRAP, T-BAM, CD40 Ligand or CD40L) is a 34–39 kilodalton type II integral membrane protein. Initially CD40L was reported to be expressed …

CD40 ligand (CD40L, also known as TNFSF5 or CD154) is a gene residing on the X chromosome that encodes for a critical costimulatory molecule expressed on T cells, providing the …

The CD40 receptor and its ligand CD40L is one of the most critical molecular pairs of the stimulatory immune checkpoints. Both CD40 and CD40L have a membrane form and a soluble …

CD40 binds its ligand CD40L, which is transiently expressed on T cells and other non-immune cells under inflammatory conditions. A wide spectrum of molecular and cellular processes is …