2023年7月10日 · Salicylate toxicity is a medical emergency. Intentional ingestion or accidental overdose can cause severe metabolic derangements, making treatment difficult. Co-ingestion of other medications can further complicate management. Salicylates are widely available over the counter medications.

Use restrictions (low), Endocrine disruption (low), and Irritation (skin, eyes, or lungs) (low) Benzyl Salicylate is an ester of benzyl alcohol and salicylic acid; this ingredient has been associated with allergies and contact dermatitis. See how this product scores for common concerns.

Benzyl salicylate is not a toxic skincare ingredient, meaning it doesn’t pose risk to health. However, it can cause skin irritation or lead to an allergic skin reaction. Skincare Lab considers this a poor ingredient since it has limited direct skin benefits and can irritate the skin.

We performed an ab initio next-generation risk assessment (NGRA) for a fragrance ingredient, benzyl salicylate (BSal), to demonstrate how cosmetic ingredients can be evaluated for systemic toxicity endpoints based on non-animal approaches.

2019年6月26日 · In an acute dermal toxicity study, Benzyl Salicylate was applied (neat) to the clipped area of three albino rabbits at doses of 5, 10, or 20 g/kg and held in close contact with the skin under a plastic wrap and bandages for an exposure period of

potential endocrine disrupting properties of Benzyl Salicylate, does the SCCS consider Benzyl Salicylate safe when used up to the maximum concentrations provided in the dossier submission by the Benzyl Salicylate Consortium? Based on the assessment of data provided and taking under consideration the concerns

2020年6月24日 · This article highlights the risk factors for salicylate toxicity; reviews the pathophysiological effects; notes the hidden sources of salicylates, including foods, drugs, and topical ointments...

In an acute dermal toxicity study, three albino rabbits were administered Benzyl Salicylate (neat) to a clipped area of skin at doses of 5, 10, or 20 g/kg for 24 hours. 16 Animals were observed for seven days.

Salicylate toxicity is a complex problem that may develop with either acute or chronic exposure to salicylates. Salicylates are found in over-the-counter medications including aspirin, bismuth subsalicylate, effervescent antacids, ointments, liniments, and oil of wintergreen (methyl salicylate) and alternative medication products (e.g., willow ...

2021年3月21日 · Benzyl salicylate is used as a fragrance ingredient and an ultraviolet light absorber, but its toxicity is unknown. Therefore, toxicity tests and hazard classification were conducted for screening assessment under the Japanese Chemical Substances Control Law.