Research led by the Chiba Cancer Center Research Institute in Japan has discovered a surprising way cancer evades the immune ...
通过线粒体转移,癌细胞不仅实现了对T细胞功能的精确抑制,还为其免疫逃逸增加了一道屏障。该研究进一步指出,这种机制与免疫治疗效果不佳密切相关,尤其是在携带大量mtDNA突变的患者中,免疫检查点抑制剂的疗效显著降低。
SON-1010, after receipt of data suggesting clinical benefit when administered as a monotherapy in patients with advanced solid tumors, enters combination evaluation with trabectedin (Yondelis®) with ...
The targeting of telomeres offers promise for new cancer therapies, which can be aimed at disrupting the mechanisms that ...
Immunotherapy, cancer treatments that alter the immune system, making it better apt to fight tumor cells, have provided novel ...
The tissue adjacent to a tumor behaves differently than areas farther away: The tumor's cancerous cells influence their surroundings, blocking the body's immune defenses and creating a sort of haven ...
The tissue adjacent to a tumor behaves differently than areas farther away. The tumor's cancerous cells influence their ...
Researchers identify distinct molecular and immune profiles that impact the prognosis of patients with metastatic pancreatic ductal adenocarcinoma.
Researchers in the group of Associate Professor Ninib Baryawno, Department of Women's and Children's Health, KI, have ...
On track to report updated overall survival data for CAN-2409 from phase 2a clinical trials in pancreatic ductal adenocarcinoma (PDAC) and ...