D tumoroid models transform cancer research, accurately reflecting tumor biology and enabling effective drug testing and ...

The programme – spearheaded by The Academic Respiratory Initiative for Pulmonary Health (Tariph) Centre under LKCMedicine – ...

Researchers reveal how targeting HIF2 could transform the treatment of idiopathic pulmonary fibrosis (IPF), offering hope for ...

Centre, a national research platform led by Nanyang Technological University, Singapore’s (NTU Singapore) Lee Kong Chian School of Medicine (LKCMedicine), will lead a multi-institutional research ...

Disorders of surfactant protein biology cause dysfunction of alveolar type 2 cells and can lead to interstitial lung disease. This study describes the development of genetically manipulable, mature ...

Lung disease modeling and dissection of the underlying mechanisms remain challenging due to complexities in deriving and maintaining human AT2 cells ex vivo. Here, we describe the development of ...

1Department of Medicine, Columbia Center for Human Development, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, New York. 2Herbert Irving Comprehensive ...

Using a large-scale library of TC organoids they developed, the researchers performed comprehensive comparative analyses of chemo-sensitive and chemo-resistant cells. Their efforts shed light on ...

A team has now succeeded for the first time in cultivating stable tumor organoids directly from blood samples of breast cancer patients. Using these mini-tumors, the researchers were able to ...

A team from the German Cancer Research Center (DKFZ), the Heidelberg Stem Cell Institute HI-STEM and the NCT Heidelberg has now succeeded for the first time in cultivating stable tumor organoids ...

Thanks to the successful cultivation of the organoids, Trumpp's interdisciplinary research team—in close collaboration with the experts of the CATCH trial—was able to identify a key signaling ...