Organoids can be derived from a variety of cell types, such as human primary progenitor cells, pluripotent stem cells, or tumor-derived cells and can be co-cultured with immune or microbial cells to ...

31, 2024 — Researchers have shown that the IGFBP3 protein plays a relevant role in human lung development. The results of the study, which used organoids derived from embryonic lungs ...

Lung disease modeling and dissection of the underlying mechanisms remain challenging due to complexities in deriving and maintaining human AT2 cells ex vivo. Here, we describe the development of ...

Disorders of surfactant protein biology cause dysfunction of alveolar type 2 cells and can lead to interstitial lung disease. This study describes the development of genetically manipulable, mature ...

31, 2024 — Researchers have shown that the IGFBP3 protein plays a relevant role in human lung development. The results of the study, which used organoids derived from embryonic lungs ...

Researchers reveal how targeting HIF2 could transform the treatment of idiopathic pulmonary fibrosis (IPF), offering hope for ...

Dispatch: Comparison of Contemporary and Historic Highly Pathogenic Avian Influenza A(H5N1) Virus Replication in Human Lung Organoids. Image Credit: Credit: NIAID and CDC In a ...

ACROBiosystems provides comprehensive Organoid Toolbox solutions through sophisticated technology and experienced services, such as ready-to-use iPSC-derived organoids, cryopreserved organoids ...

The programme – spearheaded by The Academic Respiratory Initiative for Pulmonary Health (Tariph) Centre under LKCMedicine – ...

Lung cancer liver metastases are tumors that form in the liver from cancer cells that have broken away from the primary cancer and spread through the blood or lymphatic system. The liver is a common ...

The gold standard for finding lung cancer early is computed tomography (CT) lung cancer screening. However, this is limited to people who have smoked. Currently, there are more non-smokers (never ...