Witnessing the so-called “cringe” media presence of tech billionaires who wield more power than they should is like watching a car accident—tragic but impossible to look away from. A recent opinion ...
Frizzled (FZD) proteins are the principal receptors of the Wnt signaling pathway. However, whether Wnt ligands induce FZD endocytosis and degradation remains elusive. The transmembrane E3 ubiquitin ...