X-Linked Adrenoleukodystrophy (X-ALD) is a genetic disorder caused by mutations in the ABCD1 gene, which is responsible for transporting very-long-chain fatty acids ...

Nitro-fatty acids (NO 2-FAs) are a class of bioactive lipids that have garnered significant attention due to their potential therapeutic effects, particularly in inflammation and immune response ...

"ALD is a disease that prevents the body from breaking down long-chain fatty acids, causing them to build ... their son had X-linked Adrenoleukodystrophy, or ALD, a rare and serious genetic ...

Quentin M. Anstee, B.Sc., M.B.B.S., Ph.D., M.R.C.P.; Ann K. Daly, B.Sc., Ph.D.; Christopher P. Day, B.A.,M.B., B.Chir.,M.A. (Cambridge), Ph.D.,M.D., F.R.C.P., F.Med ...

ALD prevents the body from breaking down very long chain fatty acids (VLCFAs) which causes damage to the myelin sheath, the membrane that surrounds nerve fibers in the brain and spinal cord.

HSCT may be a suitable treatment for X-linked ALD adults with early signs of cerebral involvement. Very long-chain fatty acid levels and adrenoleukodystrophy protein (ALDP)-deficiency are strongly ...

ALD prevents the body from breaking down very long chain fatty acids (VLCFAs ... treatment options in the next five to 10 years. X-Linked Adrenoleukodystrophy (ALD) is a rare genetic disorder ...