CRISPR-Cas systems have been exploited for targeted genome editing. Applying the CRISPR-Cas9 system to edit high GC content genomes has been challenging due to its high off-target activity.
CRISPR is short for ‘clustered regularly interspaced short palindromic repeats.’ The term refers to a series of repetitive patterns in the DNA of bacteria and archaea that were extensively researched ...
CRISPR-Cas9 genome editing exploits the CRISPR-Cas system to modify a genome in a targeted manner. Guided by RNA, the Cas9 endonuclease breaks DNA at a target sequence. Imprecise repair of the ...
13, 2025 (GLOBE NEWSWIRE) -- CRISPR Therapeutics (Nasdaq ... driven by strong patient demand and robust payer and system support. Continue advancing our pipeline candidates, with several key ...