Cellular damage occurs when sensitized T-lymphocytes and/or autoantibodies bind to thyroid cell membranes causing cell lysis and inflammatory reactions. Alterations in thyroid gland function ...
The International Consensus on ANA Patterns (ICAP) initiative recently described the clinical relevance and associated autoantibodies of HEp-2 indirect immunofluorescence (HEp-2 IIF) patterns.1 We ...
These recommendations are based on current knowledge and can enable harmonisation of local algorithms for testing and evaluation of ANA and related autoantibodies. Last but not least, new more ...
The final, formatted version of the article will be published soon. Tumor-associated antigens (TAA) are proteins expressed during the growth and development of tumor cells, and TAA autoantibodies ...
We tested for the presence and clinical features of autoantibodies targeting these receptors and compared these with autoantibodies known to be associated with COVID‐19. Amongst patients hospitalised ...
Blood samples from these patients were screened for the presence of novel autoantibodies, revealing unique autoantibody specificity against 200-kd and 100-kd proteins (anti-200/100 autoantibodies ...
Background Sporadic inclusion body myositis (sIBM) is an intractable muscle disease that frequently affects elderly people. Autoantibodies recognising cytosolic 5’-nucleotidase 1A (cN1A) were found in ...
T cells play a pivotal role in the immune system by transforming into powerful effector cells that combat pathogens. This transformation requires rapid proliferation, during which DNA replication ...
An autoantibody is an antibody directed against the body’s cells. Antibodies are designed to attack invading pathogens, like viruses and bacteria. Autoantibodies occur when the immune system becomes ...