IRAP (Insulin-Regulated Aminopeptidase): An enzyme that regulates various biological processes, including insulin signaling and peptide metabolism. Allosteric Inhibition: A form of enzyme ...

The collaboration will utilize Atavistik's AMPS platform to identify novel allosteric binders against two undisclosed targets selected by Pfizer (NYSE:PFE), which will also have an option to ...

Despite the global focus on this area, identifying enzyme activators remains challenging due to their reliance on allosteric modulation—a mechanism that is viable in fewer than 10% of proteins.