Tumor cell dormancy refers to an adaptive response of a cancer cell, after it detaches from the primary tumor and disseminates throughout the body. These disseminated tumor cells (DTCs ...
Figure 8: Schematic of the Mary-X xenograft/spheroidgenesis model of tumor dormancy Schematic depicts the Mary-X xenograft/spheroidgenesis sequence (A–G) which initiates tumor dormancy in vivo ...
“Our research identified a key mechanism used by cancer cells to evade therapy by remaining in a dormant state, hibernating before they ‘wake up’ years later and begin to rapidly divide agai ...
Future Oncol. 2011;7(11):1285-1297. More broadly, DTC dormancy creates a variety of clinical challenges to understanding and treating bone metastases. It is not standard practice to evaluate bone ...
These models are being used to study critical questions of tumor heterogeneity, dormancy and recurrence with a focus on the treatment of metastatic triple negative breast cancer. The research ...
Breast cancer can resurface after remaining dormant for 15 years following successful treatment, a study has found. Women with large tumours and cancer that had spread to the lymph nodes had the ...
The University of Sheffield was given the funding to look into dormant cancer cells and develop new treatments for myeloma, a type of blood cancer. Myeloma affects 6,000 people in the UK every ...