The induced tau lesions propagate from the injection site to other regions in aconnectome-dependent manner. This phenomenon strongly supports the view that tau protein has the ability to transfer as ...

For each structural strain of tau fibrils, they identified amino acids without which the strain cannot form its signature ...

Tau is a protein that builds up and moves between nerve cells in the brains of people living with Alzheimer’s disease, causing damage. Professor Mudher is using clever genetic manipulation in fruit ...

The Amyloid—Tangle Connection. Aβ aggregates (green) hyper-excite neurons in tau epicenters and connected regions, strengthening that connectivity. This pushes tau propagation from one region to ...

"Assembled tau associates with EVs in the central nervous system of individuals with AD, which is linked to its clearance and prion-like propagation. However, the identities of the assembled tau ...