also known as TNF ligand superfamily member 13), or both, represents a different paradigm for B-cell targeting in SLE (reviewed elsewhere 37). Human BAFF signals through three different receptors ...

Lupus nephritis (LN) is one of the most serious complications of systemic lupus erythematosus ... that are more targeted and less toxic. CD40–CD40L signaling may regulate both the initiation ...

In contrast, after adding 20 mg/kg of monoclonal antibody against CD40 ligand to the regimen on days 0 and 2, we observed four thromboembolic complications in nine recipients. These included two ...

Systemic lupus erythematosus is a complex autoimmune disorder affecting multiple organ systems. Glomerulonephritis leading to severe proteinuria, chronic renal failure and end-stage renal disease ...