The images before and after quenching of CMS-NPs-Cy3 (see the 'Preparation of fluorescent mesoporous silica nanoparticles' section) were processed by Particle-in-cell-3D using different values for ...

The procedure uses lipid nanoparticles (LNPs) to carry genetic instructions to the stem cells. The LNPs have targeting ligands attached—molecules designed to find specific target cells.

The key to that scientific leap? Nanoparticles, tiny technology that’s able to carry tumor-targeting genes directly to immune cells still within the body and program them to destroy cancer. In a proof ...

Aim: This study examines the absolute quantification of particle uptake into cells. Methods: We developed a novel method to analyze stacks of confocal fluorescence images of single cells ...

A fluorescence filter is placed between the cell channel and the microscope ... (Image: Adapted from DOI:10.3791/58731) Sample preparation: The nanoparticle sample is diluted to an appropriate ...

In animal experiments, these nanoparticles demonstrated the ability to inhibit leukemia cell growth and significantly improve ...

Researchers encapsulated Bmi-1 siRNA within liposomes, attaching AS1411 to ensure the nanoparticles specifically bind to tumor cells. The resulting particles demonstrated a drug-loading capacity ...