Jude Children's Research Hospital identified malformed regions of the cerebellum in laboratory models and patients with 22q and found that these malformations were caused by improper skull formation.

"In my mind, it's like a stepping stone. We hope to follow this chain of events from the malformed skull to the underdeveloped flocculus and paraflocculus to the auditory cortex dysfunction ...

Jude Department of Developmental Neurobiology published in Nature Communications revealed a gene deleted in 22q11.2 deletion syndrome results in malformed ... of a local skull deformity.

This malformation causes an abnormal depression in the skull that can impair brain development. The left photo shows a part of a normal mouse brain, and the right photo shows a part of a mouse ...