The organoids, based on pluripotent stem cells, reproduce in 3D a specific tissue, in this case the lung mucosa, which can be ...

31, 2024 — Researchers have shown that the IGFBP3 protein plays a relevant role in human lung development. The results of the study, which used organoids derived from embryonic lungs ...

The programme – spearheaded by The Academic Respiratory Initiative for Pulmonary Health (Tariph) Centre under LKCMedicine – ...

This allows researchers to model organ-specific diseases, such as inflammatory bowel disease using gastrointestinal organoids, cystic fibrosis using lung organoids, and bladder cancer using urothelial ...

To address these fundamental questions, we employ a multidisciplinary approach integrating genetic mouse models with lineage-tracing techniques, primary mouse and human lung organoids with genetic ...

Researchers reveal how targeting HIF2 could transform the treatment of idiopathic pulmonary fibrosis (IPF), offering hope for ...

Dispatch: Comparison of Contemporary and Historic Highly Pathogenic Avian Influenza A(H5N1) Virus Replication in Human Lung Organoids. Image Credit: Credit: NIAID and CDC In a ...

Using a large-scale library of TC organoids they developed, the researchers performed comprehensive comparative analyses of chemo-sensitive and chemo-resistant cells. Their efforts shed light on ...

A team from the German Cancer Research Center (DKFZ), the Heidelberg Stem Cell Institute HI-STEM and the NCT Heidelberg has now succeeded for the first time in cultivating stable tumor organoids ...