Levodopa is the most efficacious agent for the treatment of motor features of Parkinson's disease but its chronic use is associated with the development of motor complications. Mounting evidence ...

Parkinson’s disease is a progressive neurodegenerative disorder that affects millions of people worldwide. In the United ...

For decades, doctors have treated Parkinson's by giving patients levodopa, the inactive substance in the brain that once converted makes dopamine. "Levodopa is a replacement strategy. We all make ...

Inhibikase Therapeutics said on Wednesday it would stop development of its experimental Parkinson's disease drug after it failed to improve patients' ability to carry out daily tasks such as eating ...

Rates of Parkinson’s disease are rising for reasons which remain unclear, yet it remains an incurable illness. Right now, the main treatment available to patients is levodopa, a therapy which ...

Researchers uncovered new findings about involuntary muscle movements that come with long-term administration of Parkinson's drug levodopa. University of Arizona researchers have revealed new ...

MM PD market growth will be driven by advancements in innovative therapies, including the first DMTs, and a growing patient ...

Diet may also help your body handle Parkinson’s medications better. Research suggests that diet may play a role in boosting the efficacy of drugs like levodopa and in helping to manage side effects.

Problems with chemical messengers like dopamine were tied to posture issues in SMA in a mouse study, but levodopa therapy may ease symptoms.

However, over a number of years, the brain of a Parkinson’s patient adapts to the levodopa treatment, and long term levodopa therapy can lead to dyskinesia, explained lead author Abhilasha ...

A robust evaluation of the continuous dopaminergic stimulation hypothesis may require a longer acting levodopa preparation. In fluctuating Parkinson's disease (PD) patients, treatment of PD using ...

Over the years, the brain of a Parkinson's patient adapts to the levodopa treatment, which is why levodopa causes dyskinesia in the long term, said Abhilasha Vishwanath, the study's lead author ...