The hair follicle is a major repository for epidermal stem cells. Learning more about the processes that regulate the differentiation of these cells will improve the prospects for skin replacement ...

2 The body replenishes these cells through epidermal stem cells (EpSCs) in the basal layer of the epidermis. The dermis is enriched in extracellular matrix (ECM) proteins, fibroblasts, blood vessels, ...

As a self-renewing organ maintained by multiple distinct stem cell populations, the skin epidermis represents an outstanding, clinically highly relevant research paradigm to address these questions.

But only some of the stem cells that will ultimately patch her up are normally dedicated to replenishing the epidermis that ...

His goal is to identify genes and gene pathways that can be used as targets in cancer therapy with a particular focus on the regulators of the balance between stem cell renewal and differentiation. Dr ...