Allosteric regulation refers to the process by which ... This mechanism is essential for many biological processes, including enzyme activity and signal transduction. Recent research has focused ...

Allosteric regulation is a crucial mechanism by which proteins, including hemoglobin, modulate their activity in response to environmental changes. Hemoglobin, the protein responsible for ...

Enzyme activity is tightly regulated in living organisms to maintain homeostasis and respond to changing conditions. Enzymes can be regulated by various means, such as allosteric regulation (binding ...

Innovative therapies revive a once-undruggable mitochondrial aging regulator through a revolutionary enzyme activation ...

While enzyme and allosteric regulation which controls metabolism was suppressed in typical mice during feeding, we were surprised to find that the reverse occurred in obese mice and that this ...

The molecular mechanisms that enzymes use to carry out catalysis are often very selective, which makes me appreciate how much of a powerful force evolution is. Allosteric regulation of enzymes also ...

She was an early investigator to adopt methods of of mass spectrometry and functional proteomics to identify targets of signaling pathways, and the use of hydrogen-deuterium exchange mass spectrometry ...

Notably, SIRT3, the major mitochondrial sirtuin enzyme, plays a critical role in determining health span and lifespan through its regulation ... the absence of a known allosteric site.