The fact that their groundbreaking paper 1 was published in a cancer journal (the British Journal of Cancer in 1972) set the scene for what followed on the role of apoptosis in cancer biology.

the mRNA expression of some genes in the kidney linked with apoptosis (e.g., caspase 3, caspase 8, caspase 9, and cychrome c), and correlated with oxidative stress (e.g., Nrf-2, GCLC, NQO1, HO-1, ...

1 In a seminal paper Kerr, Wyllie, and Currie2 later coined the word apoptosis to describe this form of death and went on to show that it was a widespread process in nature, occurring both during ...

bAcademic Neurology Unit, Section of Neuroscience, Division of Genomic Medicine, The Medical School, University of Sheffield, Sheffield, UK There is increasing evidence that a programmed mechanism of ...

Department of Medicine 1, University of Erlangen-Nuremberg, Erlangen ... has been associated with chronic inflammation as seen in patients with Crohn's disease and ulcerative colitis. While until ...

The mechanisms accounting for the aberrant accumulation of fibroblasts during fibrotic repair are poorly understood, although evidence supports a role for fibroblast resistance to apoptosis as a ...

Cells containing DNA strand breaks, a marker of apoptosis, were identified by terminal deoxyuridine nucleotidyl nick end labelling (TUNEL). RESULTS There were fewer TUNEL positive epithelial cells in ...

Nanjing Reju Therapeutics Inc. has described tumor necrosis factor receptor type 1-associated DEATH domain protein (TRADD) inhibitors reported to be useful for the treatment of inflammatory-related ...